SOFIDERM is a biphase, transparent, sterile, highly-elastic gel of stabilized hyaluronic acid (BDDE) of non-animal origin intended to contour corrections and wrinkle filling.

BEAUTY STARTS HERE
Sofiderm is based on microbial fermentation. The implant is free of protein and toxins, which guarantees its safety. Raw materials for Sofiderm production are approved by FDA (USA), EDQM (Europe) and Roszdravnadzor (Russia). BDDE is almost completely consumed in the cross-linking reaction, so the linking is very homogeneous, and there is almost no residual BDDE in the final product (< 1 ppm).
Materials
German quality: MCLPE manufacture technology developed by the Zcube research group (Germany). This is an innovative and advanced technology that combines high cross-linking efficiency and high HA purity, which results in a 3D gel with a more rigid structure and long-term effect.

Manufacturing

The factory implements the quality management system according to EN ISO 13485: 2016, ISO 9001 and complies with the international GMP standards.
Production control at each stage ensures quality and safety.
Equipment
The existing range of fillers provides various density: Finelines, Derm, Deep, Derm Plus, Derm Sub-Skin.
Composition
Cross-linked hyaluronic gel
20 mg / ml
0.1-0.15 mm
200.000 ml
Concentration
No. of particles
1 ml / 2 ml
30Gx2
3-8 months
Package
Needle size
Persistence
Application
SOFIDERM FINELINES
For patients with extra thin skin, surface wrinkles, forehead, perioral zone, crow's feet, neck, reinforcement of hand skin, cheeks, earlobes, temporal region.
Composition
Cross-linked hyaluronic gel
20 mg / ml
0.15-0.28 mm
100.000 ml
No. of particles
1 ml / 2 ml
27Gx2
6-10 months
Package
Needle size
Persistence
Application
SOFIDERM DERM
Lip volume, feeble nosolabial and melomental folds, buccal jugal furrow, parotic zone
Composition
Cross-linked hyaluronic gel
20 mg / ml
0.28-0.5mm
10.000 ml
Concentration
Particle size
Particle size
1 ml / 2 ml
27Gx2
8-12 months
Package
Needle size
Persistence
Application
SOFIDERM DEEP
Zygomatic region, lip outline and volume, deep nasolabial folds, paraorbital zone, supraperiosteally, perioral region, temporal zone, forehead.
Composition
Cross-linked hyaluronic gel
20 mg / ml
0.5-1.25 mm
5.000 ml
Concentration
Particle size
No. of particles
1 ml / 2 ml / 10 ml / 20 ml
25Gx2
10-14 months
Package
Needle size
Persistence
Application
SOFIDERM DERM PLUS
Volumizer for filling large volumes of face and body, forming the face oval, chin, nose, intimate zones, jugal zone, bony orbital margin, superciliary region, lower jaw corners, subcutaneously, supraperiosteally, temporal zone.
Composition
Cross-linked hyaluronic gel
20 mg / ml
1.25-2.0 mm
2.000 ml
Concentration
Particle size
No. of particles
10 ml / 20 ml
No needles
12-24 months
Package
Needle size
Persistence
Application
SOFIDERM SUBSKIN
Volumizer for filling large volumes of body, cruroplastic, plastic reconstruction of gluteal region, upper and lower limbs.
Concentration
Particle size
Particle size
Long-term persistence
According to a 24-week clinical randomized controlled trial, the percentage of improvement in implantation sites (nasolabial wrinkles, crow’s feet, forehead wrinkles, glabellar wrinkles, etc.) varies within 65.1% to 82.9%.
High rate of satisfaction
Sofiderm demonstrates a high rate of patients’ and doctors’ satisfaction with the natural volumes immediately after treatment.
Enhancend Purification
Crossliking
MCLPE Technology guarantees a long-term effect and highest safety. It is characterized by improved purification system and high efficiency of hyaluronic acid cross-linking.
(Multiphase Cross Liking&Purification Enhancement)
MCLPE Technology
Sofiderm fillers have a unique particle size for meeting any requirements.